Know When to Switch Therapy and When to Monitor for Serotonin Syndrome

October 2016

Drug interaction alerts in your EHR continue to cause confusion about when to change therapy due to the risk of serotonin syndrome.

Think of serotonin syndrome as "serotonin overload" caused by high doses...multiple serotonergic drugs...or drug interactions.

The higher the load, the greater the risk.

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Table of Contents

Influenza Be Aware of Differences Among Fluad, Fluzone High-Dose and a Standard Flu Shot
Vaccines Feel Comfortable Giving Any Flu Vaccine to Patients With an Egg Allergy
Diabetes Don't Jump to Insulin Even if Glucose is Very High in New-Onset Type 2 Diabetes
Diabetes Watch for Gallbladder Problems in Patients Using GLP-1 Agonists
Antithrombotics Look for Atrial Fib Patients Who May Need Anticoagulation
Opioids Avoid Using Opioids and Benzodiazepines Together
Adverse Events Know When to Switch Therapy and When to Monitor for Serotonin Syndrome
Adverse Events Limit the Dose of Hydroxyzine to 100 mg Per Day in Adults
Pregnancy Explain Why Acetaminophen is Still Okay in Pregnancy
Infectious Diseases Use the Nucleic Acid Amplification Test to Identify Tuberculosis Patients Sooner
Gout Don't Use the New Gout Med Zurampic Alone
Medicare Be Aware of What's New For 2017 Medicare Part D Plans