risk of acute kidney injury when adding an NSAID to a diuretic plus an ACEI or ARB
You'll hear more about the risk of acute kidney injury when adding an NSAID to a diuretic plus an ACEI or ARB.
Combining all three agents creates a "triple whammy" to impair kidney function...and sometimes the kidneys can't compensate.
This is especially true in patients at risk due to age over 65, chronic kidney disease, or systolic heart failure.
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